V-type proton ATPase 21 kDa proteolipid subunit c''
BE0009945ProteinHumansATP6V0B
Proton-conducting pore forming subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (PubMed:33065002).
- Gene name
- ATP6V0B
- UniProtKB entry
- Q99437Swiss-Prot
- Cellular location
- Cytoplasmic vesicle, clathrin-coated vesicle membrane
- Residues / weight
- 205 residues · 21,406 Da
- Also known as
- ATP6F · hATPL · V-ATPase 21 kDa proteolipid subunit c'' · Vacuolar proton pump 21 kDa proteolipid subunit c''
Resolves to
Pharmacology
What you can answer from here — as of September 03, 2024
Which compounds in development act on V-type proton ATPase 21 kDa proteolipid subunit c'', and which indications are they being tested in?
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