V-type proton ATPase 16 kDa proteolipid subunit c

BE0009948ProteinHumansATP6V0C

Proton-conducting pore forming subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (PubMed:33065002, PubMed:36074901).

Gene name
ATP6V0C
UniProtKB entry
P27449Swiss-Prot
Cellular location
Cytoplasmic vesicle, clathrin-coated vesicle membrane
Residues / weight
155 residues · 15,736 Da
Also known as
ATP6C · ATP6L · ATPL · V-ATPase 16 kDa proteolipid subunit c · Vacuolar proton pump 16 kDa proteolipid subunit c

Resolves to

Pharmacology

What you can answer from here — as of September 03, 2024

15GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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8+ReferencesStructured and connected to the statements they support
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Which compounds in development act on V-type proton ATPase 16 kDa proteolipid subunit c, and which indications are they being tested in?

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