V-type proton ATPase 116 kDa subunit a 4
BE0009949ProteinHumansATP6V0A4
Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (By similarity).
- Gene name
- ATP6V0A4
- UniProtKB entry
- Q9HBG4Swiss-Prot
- Cellular location
- Apical cell membrane
- Residues / weight
- 840 residues · 96,385 Da
- Also known as
- ATP6N1B · ATP6N2 · V-ATPase 116 kDa isoform a 4 · Vacuolar proton translocating ATPase 116 kDa subunit a isoform 4 · Vacuolar proton translocating ATPase 116 kDa subunit a kidney isoform
Resolves to
Pharmacology
What you can answer from here — as of September 03, 2024
Which compounds in development act on V-type proton ATPase 116 kDa subunit a 4, and which indications are they being tested in?
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