V-type proton ATPase 116 kDa subunit a 2

BE0009950ProteinHumansATP6V0A2

Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (By similarity).

Gene name
ATP6V0A2
UniProtKB entry
Q9Y487Swiss-Prot
Cellular location
Cell membrane
Residues / weight
856 residues · 98,081 Da
Also known as
Lysosomal H(+)-transporting ATPase V0 subunit a 2 · TJ6 · V-ATPase 116 kDa subunit a 2 · Vacuolar proton translocating ATPase 116 kDa subunit a isoform 2

Resolves to

Pharmacology

What you can answer from here — as of September 03, 2024

5GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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11+ReferencesStructured and connected to the statements they support
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Which compounds in development act on V-type proton ATPase 116 kDa subunit a 2, and which indications are they being tested in?

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