V-type proton ATPase subunit B, kidney isoform
BE0009951ProteinHumansATP6V1B1
Non-catalytic subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (PubMed:16769747).
- Gene name
- ATP6V1B1
- UniProtKB entry
- P15313Swiss-Prot
- Cellular location
- Apical cell membrane
- Residues / weight
- 513 residues · 56,833 Da
- Also known as
- ATP6B1 · Endomembrane proton pump 58 kDa subunit · V-ATPase subunit B 1 · Vacuolar proton pump subunit B 1 · VATB
Resolves to
Pharmacology
What you can answer from here — as of May 15, 2020
Which compounds in development act on V-type proton ATPase subunit B, kidney isoform, and which indications are they being tested in?
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