V-type proton ATPase subunit D

BE0009956ProteinHumansATP6V1D

Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (PubMed:33065002).

Gene name
ATP6V1D
UniProtKB entry
Q9Y5K8Swiss-Prot
Cellular location
Membrane
Residues / weight
247 residues · 28,263 Da
Also known as
ATP6M · V-ATPase 28 kDa accessory protein · V-ATPase subunit D · Vacuolar proton pump subunit D · VATD

Resolves to

Protein
UniProtQ9Y5K8UniProt nameVATD_HUMAN
Gene
HGNCHGNC:13527NCBI Gene51382GeneCardsATP6V1D
Pharmacology
KEGGhsa:51382
Structure
PDB6WLZPDB6WM2PDB6WM3

What you can answer from here — as of May 15, 2020

17GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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6+ReferencesStructured and connected to the statements they support
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Which compounds in development act on V-type proton ATPase subunit D, and which indications are they being tested in?

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