V-type proton ATPase subunit F
BE0009957ProteinHumansATP6V1F
Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (PubMed:33065002).
- Gene name
- ATP6V1F
- UniProtKB entry
- Q16864Swiss-Prot
- Cellular location
- Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane
- Residues / weight
- 119 residues · 13,370 Da
- Also known as
- ATP6S14 · V-ATPase 14 kDa subunit · V-ATPase subunit F · Vacuolar proton pump subunit F · VATF
Resolves to
Pharmacology
What you can answer from here — as of May 15, 2020
Which compounds in development act on V-type proton ATPase subunit F, and which indications are they being tested in?
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