V-type proton ATPase subunit G 1

BE0009960ProteinHumansATP6V1G1

Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (PubMed:32001091, PubMed:33065002).

Gene name
ATP6V1G1
UniProtKB entry
O75348Swiss-Prot
Cellular location
Apical cell membrane
Residues / weight
118 residues · 13,757 Da
Also known as
ATP6G · ATP6G1 · ATP6J · V-ATPase 13 kDa subunit 1 · V-ATPase subunit G 1

Resolves to

Protein
UniProtO75348UniProt nameVATG1_HUMAN
Gene
HGNCHGNC:864NCBI Gene9550GeneCardsATP6V1G1
Pharmacology
KEGGhsa:9550
Structure
PDB6WLZPDB6WM2PDB6WM3

What you can answer from here — as of May 15, 2020

6GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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7+ReferencesStructured and connected to the statements they support
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Which compounds in development act on V-type proton ATPase subunit G 1, and which indications are they being tested in?

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