Integrin alpha-X

BE0009967ProteinHumansITGAX

Integrin alpha-X/beta-2 is a receptor for fibrinogen. It is acted on by 1 drug in DrugBank.

Gene name
ITGAX
UniProtKB entry
P20702Swiss-Prot
Cellular location
Cell membrane
Residues / weight
1,163 residues · 127,828 Da
Also known as
CD11 antigen-like family member C · CD11C · Leu M5 · Leukocyte adhesion glycoprotein p150,95 alpha chain · Leukocyte adhesion receptor p150,95

Resolves to

Protein
UniProtP20702UniProt nameITAX_HUMAN
Gene
HGNCHGNC:6152NCBI Gene3687GeneCardsITGAX
Pharmacology
KEGGhsa:3687
Structure
PDB1N3YPDB2LUVPDB3K6S
Drugs

What you can answer from here — as of May 15, 2020

1DrugApproved to experimental, with action, bond type and pharmacological action
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5Clinical trialsTrials of drugs acting on it, by phase and status
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8GO termsFunction, process and component, as structured annotations
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6Pfam domainsDomain architecture mapped to Pfam families and clans
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9+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Integrin alpha-X, how selective are they, and which programs against it are still in active trials?

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