Plasma membrane calcium-transporting ATPase 1

BE0009968ProteinHumansATP2B1

Catalyzes the hydrolysis of ATP coupled with the transport of calcium from the cytoplasm to the extracellular space thereby maintaining intracellular calcium homeostasis (PubMed:35358416).

Gene name
ATP2B1
UniProtKB entry
P20020Swiss-Prot
Cellular location
Cell membrane
Residues / weight
1,220 residues · 134,684 Da
Also known as
7.2.2.10 · Plasma membrane calcium ATPase isoform 1 · Plasma membrane calcium pump isoform 1 · PMCA1

Resolves to

Protein
UniProtP20020UniProt nameAT2B1_HUMAN
Gene
HGNCHGNC:814NCBI Gene490GeneCardsATP2B1
Pharmacology
KEGGhsa:490
Structure
PDB6A69

What you can answer from here — as of May 15, 2020

17GO termsFunction, process and component, as structured annotations
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6Pfam domainsDomain architecture mapped to Pfam families and clans
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24+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Plasma membrane calcium-transporting ATPase 1, and which indications are they being tested in?

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