Plasma membrane calcium-transporting ATPase 2

BE0009969ProteinHumansATP2B2

ATP-driven Ca(2+) ion pump involved in the maintenance of basal intracellular Ca(2+) levels in specialized cells of cerebellar circuit and vestibular and cochlear systems (PubMed:15829536, PubMed:17234811).

Gene name
ATP2B2
UniProtKB entry
Q01814Swiss-Prot
Cellular location
Cell membrane
Residues / weight
1,243 residues · 136,875 Da
Also known as
7.2.2.10 · Plasma membrane calcium ATPase isoform 2 · Plasma membrane calcium pump isoform 2 · PMCA2

Resolves to

Protein
UniProtQ01814UniProt nameAT2B2_HUMAN
Gene
HGNCHGNC:815NCBI Gene491GeneCardsATP2B2
Pharmacology
KEGGhsa:491

What you can answer from here — as of May 15, 2020

1Clinical trialTrials of drugs acting on it, by phase and status
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15GO termsFunction, process and component, as structured annotations
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6Pfam domainsDomain architecture mapped to Pfam families and clans
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9+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Plasma membrane calcium-transporting ATPase 2, and which indications are they being tested in?

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