Plasma membrane calcium-transporting ATPase 3

BE0009970ProteinHumansATP2B3

ATP-driven Ca(2+) ion pump involved in the maintenance of basal intracellular Ca(2+) levels at the presynaptic terminals (PubMed:18029012, PubMed:22912398, PubMed:25953895, PubMed:27035656).

Gene name
ATP2B3
UniProtKB entry
Q16720Swiss-Prot
Cellular location
Cell membrane
Residues / weight
1,220 residues · 134,196 Da
Also known as
7.2.2.10 · Plasma membrane calcium ATPase isoform 3 · Plasma membrane calcium pump isoform 3 · PMCA3

Resolves to

Protein
UniProtQ16720UniProt nameAT2B3_HUMAN
Gene
HGNCHGNC:816NCBI Gene492GeneCardsATP2B3
Pharmacology
KEGGhsa:492

What you can answer from here — as of May 15, 2020

9GO termsFunction, process and component, as structured annotations
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6Pfam domainsDomain architecture mapped to Pfam families and clans
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8+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Plasma membrane calcium-transporting ATPase 3, and which indications are they being tested in?

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