Neutrophil cytosol factor 2

BE0009982ProteinHumansNCF2

Subunit of the phagocyte NADPH oxidase complex that mediates the transfer of electrons from cytosolic NADPH to O2 to produce the superoxide anion (O2(-)) (PubMed:12207919, PubMed:38355798).

Gene name
NCF2
UniProtKB entry
P19878Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
526 residues · 59,761 Da
Also known as
67 kDa neutrophil oxidase factor · NADPH oxidase activator 2 · NCF-2 · Neutrophil NADPH oxidase factor 2 · NOXA2

Resolves to

Protein
UniProtP19878UniProt nameNCF2_HUMAN
Gene
HGNCHGNC:7661NCBI Gene4688GeneCardsNCF2
Pharmacology
KEGGhsa:4688
Structure
PDB1E96PDB1HH8PDB1K4U

What you can answer from here — as of May 20, 2020

9GO termsFunction, process and component, as structured annotations
Sign in
3Pfam domainsDomain architecture mapped to Pfam families and clans
Sign in
23+ReferencesStructured and connected to the statements they support
Sign in

Which compounds in development act on Neutrophil cytosol factor 2, and which indications are they being tested in?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In