5'-AMP-activated protein kinase catalytic subunit alpha-2

BE0009987ProteinHumansPRKAA2

Catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism (PubMed:17307971, PubMed:17712357).

Gene name
PRKAA2
UniProtKB entry
P54646Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
552 residues · 62,319 Da
Also known as
2.7.11.1 · ACACA kinase · Acetyl-CoA carboxylase kinase · AMPK · AMPK subunit alpha-2

Resolves to

Protein
UniProtP54646UniProt nameAAPK2_HUMAN
Gene
HGNCHGNC:9377NCBI Gene5563GeneCardsPRKAA2
Pharmacology
KEGGhsa:5563
Structure
PDB2H6DPDB2LTUPDB2YZA

What you can answer from here — as of May 20, 2020

24GO termsFunction, process and component, as structured annotations
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3Pfam domainsDomain architecture mapped to Pfam families and clans
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31+ReferencesStructured and connected to the statements they support
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Which compounds in development act on 5'-AMP-activated protein kinase catalytic subunit alpha-2, and which indications are they being tested in?

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