Calcium-transporting ATPase type 2C member 2

BE0010001ProteinHumansATP2C2

ATP-driven pump that supplies the Golgi apparatus with Ca(2+) and Mn(2+) ions, both essential cofactors for processing and trafficking of newly synthesized proteins in the secretory pathway (PubMed:15677451, PubMed:15831496, PubMed:16332677, PubMed:30923126).

Gene name
ATP2C2
UniProtKB entry
O75185Swiss-Prot
Cellular location
Golgi apparatus, trans-Golgi network membrane
Residues / weight
946 residues · 103,168 Da
Also known as
7.2.2.10 · ATPase 2C2 · Ca(2+)/Mn(2+)-ATPase 2C2 · KIAA0703 · Secretory pathway Ca(2+)-transporting ATPase type 2

Resolves to

Protein
UniProtO75185UniProt nameAT2C2_HUMAN
Gene
HGNCHGNC:29103NCBI Gene9914GeneCardsATP2C2
Pharmacology
KEGGhsa:9914

What you can answer from here — as of May 27, 2020

6GO termsFunction, process and component, as structured annotations
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4Pfam domainsDomain architecture mapped to Pfam families and clans
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6+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Calcium-transporting ATPase type 2C member 2, and which indications are they being tested in?

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