Neuropilin-2

BE0010030ProteinHumansNRP2

High affinity receptor for semaphorins 3C, 3F, VEGF-165 and VEGF-145 isoforms of VEGF, and the PLGF-2 isoform of PGF. It is acted on by 1 drug in DrugBank.

Gene name
NRP2
UniProtKB entry
O60462Swiss-Prot
Cellular location
Membrane
Residues / weight
931 residues · 104,830 Da
Also known as
Vascular endothelial cell growth factor 165 receptor 2 · VEGF165R2

Resolves to

Protein
UniProtO60462UniProt nameNRP2_HUMAN
Gene
HGNCHGNC:8005NCBI Gene8828GeneCardsNRP2
Pharmacology
KEGGhsa:8828
Structure
PDB2QQJPDB2QQKPDB2QQL
Drugs

What you can answer from here — as of January 21, 2021

1DrugApproved to experimental, with action, bond type and pharmacological action
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1Clinical trialTrials of drugs acting on it, by phase and status
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5GO termsFunction, process and component, as structured annotations
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4Pfam domainsDomain architecture mapped to Pfam families and clans
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10+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Neuropilin-2, and which indications are they being tested in?

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