Integrin beta-6

BE0010033ProteinHumansITGB6

Integrin alpha-V:beta-6 (ITGAV:ITGB6) is a receptor for fibronectin and cytotactin (PubMed:17158881, PubMed:17545607). It is acted on by 6 drugs in DrugBank.

Gene name
ITGB6
UniProtKB entry
P18564Swiss-Prot
Cellular location
Cell membrane
Residues / weight
788 residues · 85,935 Da

Resolves to

Protein
UniProtP18564UniProt nameITB6_HUMAN
Gene
HGNCHGNC:6161NCBI Gene3694GeneCardsITGB6
Pharmacology
IUPHAR/GtoPdb2460KEGGhsa:3694
Structure
PDB4UM8PDB4UM9PDB5FFG
Drugs

What you can answer from here — as of February 13, 2021

6DrugsApproved to experimental, with action, bond type and pharmacological action
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7GO termsFunction, process and component, as structured annotations
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7Pfam domainsDomain architecture mapped to Pfam families and clans
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23+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Integrin beta-6, and which indications are they being tested in?

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