Angiopoietin-related protein 3

BE0010034ProteinHumansANGPTL3

Acts in part as a hepatokine that is involved in regulation of lipid and glucose metabolism (PubMed:11788823, PubMed:12909640, PubMed:23661675, PubMed:25495645). It is acted on by 1 drug in DrugBank.

Gene name
ANGPTL3
UniProtKB entry
Q9Y5C1Swiss-Prot
Cellular location
Secreted
Residues / weight
460 residues · 53,637 Da
Also known as
ANG-5 · Angiopoietin-5 · Angiopoietin-like protein 3 · ANGPT5

Resolves to

Protein
UniProtQ9Y5C1UniProt nameANGL3_HUMAN
Gene
HGNCHGNC:491NCBI Gene27329GeneCardsANGPTL3
Pharmacology
KEGGhsa:27329
Structure
PDB6EUA
Drugs

What you can answer from here — as of February 18, 2021

1DrugApproved to experimental, with action, bond type and pharmacological action
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2GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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37+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Angiopoietin-related protein 3, how selective are they, and which programs against it are still in active trials?

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