Hyaluronidase PH-20

BE0010041ProteinHumansSPAM1

Involved in sperm-egg adhesion. It is acted on by 1 drug in DrugBank.

Gene name
SPAM1
UniProtKB entry
P38567Swiss-Prot
Cellular location
Cell membrane
Residues / weight
509 residues · 57,847 Da
Also known as
3.2.1.35 · Hyal-PH20 · HYAL3 · Hyaluronoglucosaminidase PH-20 · PH20

Resolves to

Protein
UniProtP38567UniProt nameHYALP_HUMAN
Gene
HGNCHGNC:11217NCBI Gene6677GeneCardsSPAM1
Pharmacology
KEGGhsa:6677
Structure
PDB9JUB
Drugs

What you can answer from here — as of March 02, 2021

1DrugApproved to experimental, with action, bond type and pharmacological action
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2GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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15+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Hyaluronidase PH-20, and which indications are they being tested in?

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