Vascular endothelial growth factor C

BE0010101ProteinHumansVEGFC

Growth factor active in angiogenesis, and endothelial cell growth, stimulating their proliferation and migration and also has effects on the permeability of blood vessels. It is acted on by 5 drugs in DrugBank.

Gene name
VEGFC
UniProtKB entry
P49767Swiss-Prot
Cellular location
Secreted
Residues / weight
419 residues · 46,883 Da
Also known as
Flt4 ligand · Flt4-L · Vascular endothelial growth factor-related protein · VEGF-C · VRP

Resolves to

Protein
UniProtP49767UniProt nameVEGFC_HUMAN
Gene
HGNCHGNC:12682NCBI Gene7424GeneCardsVEGFC
Pharmacology
KEGGhsa:7424
Structure
PDB2X1WPDB2X1XPDB4BSK
Drugs

What you can answer from here — as of October 28, 2021

5DrugsApproved to experimental, with action, bond type and pharmacological action
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14Clinical trialsTrials of drugs acting on it, by phase and status
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22GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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19+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Vascular endothelial growth factor C, and which indications are they being tested in?

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