Dual specificity mitogen-activated protein kinase kinase 7

BE0010123ProteinHumansMAP2K7

Dual specificity protein kinase which acts as an essential component of the MAP kinase signal transduction pathway.

Gene name
MAP2K7
UniProtKB entry
O14733Swiss-Prot
Cellular location
Nucleus
Residues / weight
419 residues · 47,484 Da
Also known as
2.7.12.2 · c-Jun N-terminal kinase kinase 2 · JNK kinase 2 · JNK-activating kinase 2 · JNKK 2

Resolves to

Protein
UniProtO14733UniProt nameMP2K7_HUMAN
Gene
HGNCHGNC:6847NCBI Gene5609GeneCardsMAP2K7
Pharmacology
IUPHAR/GtoPdb2068KEGGhsa:5609
Structure
PDB2DYLPDB3WZUPDB4UX9

What you can answer from here — as of November 09, 2021

4GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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21+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Dual specificity mitogen-activated protein kinase kinase 7, and which indications are they being tested in?

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