3-oxoacyl-[acyl-carrier-protein] reductase

BE0010128ProteinHumansCBR4

Component of the heterotetramer complex KAR (3-ketoacyl-[acyl carrier protein] reductase or 3-ketoacyl-[ACP] reductase) that forms part of the mitochondrial fatty acid synthase (mtFAS).

Gene name
CBR4
UniProtKB entry
Q8N4T8Swiss-Prot
Cellular location
Mitochondrion matrix
Residues / weight
237 residues · 25,301 Da
Also known as
1.1.1.100 · 3-ketoacyl-[acyl-carrier-protein] reductase beta subunit · Carbonyl reductase family member 4 · CBR4 · KAR beta subunit

Resolves to

Pharmacology

What you can answer from here — as of November 10, 2021

11GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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10+ReferencesStructured and connected to the statements they support
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Which compounds in development act on 3-oxoacyl-[acyl-carrier-protein] reductase, and which indications are they being tested in?

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