CD70 antigen

BE0010130ProteinHumansCD70

Expressed at the plasma membrane of B cells, it is the ligand of the CD27 receptor which is specifically expressed at the surface of T cells (PubMed:28011863, PubMed:28011864, PubMed:8387892). It is acted on by 4 drugs in DrugBank.

Gene name
CD70
UniProtKB entry
P32970Swiss-Prot
Cellular location
Cell membrane
Residues / weight
193 residues · 21,118 Da
Also known as
CD27 ligand · CD27-L · CD27L · CD27LG · TNFSF7

Resolves to

Protein
UniProtP32970UniProt nameCD70_HUMAN
Gene
HGNCHGNC:11937NCBI Gene970GeneCardsCD70
Pharmacology
KEGGhsa:970
Structure
PDB7KX0
Drugs

What you can answer from here — as of November 10, 2021

4DrugsApproved to experimental, with action, bond type and pharmacological action
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4Clinical trialsTrials of drugs acting on it, by phase and status
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5GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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16+ReferencesStructured and connected to the statements they support
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Which compounds in development act on CD70 antigen, and which indications are they being tested in?

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