Adenylate cyclase type 8

BE0010173ProteinHumansADCY8

Catalyzes the formation of cAMP in response to calcium entry leadings to cAMP signaling activation that affect processes suche as synaptic plasticity and insulin secretion.

Gene name
ADCY8
UniProtKB entry
P40145Swiss-Prot
Cellular location
Cell membrane
Residues / weight
1,251 residues · 140,121 Da
Also known as
4.6.1.1 · AC8 · Adenylate cyclase type VIII · Adenylyl cyclase 8 · ATP pyrophosphate-lyase 8

Resolves to

Protein
UniProtP40145UniProt nameADCY8_HUMAN
Gene
HGNCHGNC:239NCBI Gene114GeneCardsADCY8
Pharmacology
KEGGhsa:114

What you can answer from here — as of December 14, 2021

49GO termsFunction, process and component, as structured annotations
Sign in
3Pfam domainsDomain architecture mapped to Pfam families and clans
Sign in
5+ReferencesStructured and connected to the statements they support
Sign in

Which compounds in development act on Adenylate cyclase type 8, and which indications are they being tested in?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In