Thymic stromal lymphopoietin

BE0010181ProteinHumansTSLP

Cytokine that induces the release of T-cell-attracting chemokines from monocytes and, in particular, enhances the maturation of CD11c(+) dendritic cells. It is acted on by 3 drugs in DrugBank.

Gene name
TSLP
UniProtKB entry
Q969D9Swiss-Prot
Cellular location
Secreted
Residues / weight
159 residues · 18,141 Da

Resolves to

Protein
UniProtQ969D9UniProt nameTSLP_HUMAN
Gene
HGNCHGNC:30743NCBI Gene85480GeneCardsTSLP
Pharmacology
KEGGhsa:85480
Structure
PDB5J11PDB5J12PDB5J13
Drugs

What you can answer from here — as of December 21, 2021

3DrugsApproved to experimental, with action, bond type and pharmacological action
Sign in
3GO termsFunction, process and component, as structured annotations
Sign in
1Pfam domainDomain architecture mapped to Pfam families and clans
Sign in
13+ReferencesStructured and connected to the statements they support
Sign in

Which approved drugs act on Thymic stromal lymphopoietin, how selective are they, and which programs against it are still in active trials?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In