Interleukin-17F

BE0010184ProteinHumansIL17F

Effector cytokine of innate and adaptive immune system involved in antimicrobial host defense and maintenance of tissue integrity (PubMed:21350122). It is acted on by 2 drugs in DrugBank.

Gene name
IL17F
UniProtKB entry
Q96PD4Swiss-Prot
Cellular location
Secreted
Residues / weight
163 residues · 18,045 Da
Also known as
Cytokine ML-1 · IL-17F

Resolves to

Protein
UniProtQ96PD4UniProt nameIL17F_HUMAN
Gene
HGNCHGNC:16404NCBI Gene112744GeneCardsIL17F
Pharmacology
KEGGhsa:112744
Structure
PDB1JPYPDB3JVFPDB5N92
Drugs

What you can answer from here — as of January 11, 2022

2DrugsApproved to experimental, with action, bond type and pharmacological action
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2Clinical trialsTrials of drugs acting on it, by phase and status
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3GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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20+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Interleukin-17F, how selective are they, and which programs against it are still in active trials?

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