Lymphocyte activation gene 3 protein

BE0010189ProteinHumansLAG3

Inhibitory receptor on antigen activated T-cells (PubMed:20421648, PubMed:35761082, PubMed:7805750, PubMed:8647185). It is acted on by 9 drugs in DrugBank.

Gene name
LAG3
UniProtKB entry
P18627Swiss-Prot
Cellular location
Cell membrane
Residues / weight
525 residues · 57,448 Da
Also known as
FDC · LAG-3

Resolves to

Protein
UniProtP18627UniProt nameLAG3_HUMAN
Gene
HGNCHGNC:6476NCBI Gene3902GeneCardsLAG3
Pharmacology
KEGGhsa:3902
Structure
PDB7TZGPDB7TZHPDB7UM3
Drugs

What you can answer from here — as of March 23, 2022

9DrugsApproved to experimental, with action, bond type and pharmacological action
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17Clinical trialsTrials of drugs acting on it, by phase and status
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10GO termsFunction, process and component, as structured annotations
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21+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Lymphocyte activation gene 3 protein, how selective are they, and which programs against it are still in active trials?

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