Interleukin-1 receptor-like 2

BE0010198ProteinHumansIL1RL2

Receptor for interleukin-36 (IL36A, IL36B and IL36G). It is acted on by 2 drugs in DrugBank.

Gene name
IL1RL2
UniProtKB entry
Q9HB29Swiss-Prot
Cellular location
Membrane
Residues / weight
575 residues · 65,404 Da
Also known as
3.2.2.6 · IL-1Rrp2 · IL-36 receptor · IL-36R · IL1R-rp2

Resolves to

Protein
UniProtQ9HB29UniProt nameILRL2_HUMAN
Gene
HGNCHGNC:5999NCBI Gene8808GeneCardsIL1RL2
Pharmacology
IUPHAR/GtoPdb1736KEGGhsa:8808
Structure
PDB6U6UPDB9ETHPDB9ETI
Drugs

What you can answer from here — as of September 07, 2022

2DrugsApproved to experimental, with action, bond type and pharmacological action
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6GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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5+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Interleukin-1 receptor-like 2, how selective are they, and which programs against it are still in active trials?

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