Thiosulfate:glutathione sulfurtransferase

BE0010200ProteinHumansTSTD1

Thiosulfate:glutathione sulfurtransferase (TST) required to produce S-sulfanylglutathione (GSS(-)), a central intermediate in hydrogen sulfide metabolism (PubMed:24981631). It is acted on by 2 drugs in DrugBank.

Gene name
TSTD1
UniProtKB entry
Q8NFU3Swiss-Prot
Cellular location
Cytoplasm, perinuclear region
Residues / weight
115 residues · 12,530 Da
Also known as
2.8.1.3 · KAT · TST

Resolves to

Protein
UniProtQ8NFU3UniProt nameTSTD1_HUMAN
Gene
HGNCHGNC:35410NCBI Gene100131187GeneCardsTSTD1
Pharmacology
KEGGhsa:100131187
Structure
PDB6BEV
Drugs

What you can answer from here — as of October 05, 2022

2DrugsApproved to experimental, with action, bond type and pharmacological action
Sign in
1Pfam domainDomain architecture mapped to Pfam families and clans
Sign in
2+ReferencesStructured and connected to the statements they support
Sign in

Which approved drugs act on Thiosulfate:glutathione sulfurtransferase, how selective are they, and which programs against it are still in active trials?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In