Plasmepsin X

BE0010203ProteinPlasmodium falciparum (isolate 3D7)PMX

During the asexual blood stage, processes key proteins essential for merozoite egress and invasion of host erythrocytes (PubMed:29074775, PubMed:32109369). It is acted on by 1 drug in DrugBank.

Gene name
PMX
UniProtKB entry
Q8IAS0Swiss-Prot
Cellular location
Cytoplasmic vesicle
Residues / weight
573 residues · 65,114 Da
Also known as
3.4.23.- · PfPMX · Plasmepsin 10

Resolves to

Protein
UniProtQ8IAS0UniProt namePLM10_PLAF7
Gene
NCBI Gene2655308
Pharmacology
IUPHAR/GtoPdb3071KEGGpfa:PF3D7_0808200
Structure
PDB7RY7
Drugs

What you can answer from here — as of November 10, 2022

1DrugApproved to experimental, with action, bond type and pharmacological action
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6GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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1+ReferenceStructured and connected to the statements they support
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Which compounds in development act on Plasmepsin X, and which indications are they being tested in?

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