Fusion glycoprotein F0

BE0010206ProteinHuman respiratory syncytial virus A (strain RSS-2)F

Fusion glycoprotein F0 Inactive precursor that is cleaved at two sites by a furin-like protease to give rise to the mature F1 and F2 fusion glycoproteins. It is acted on by 1 drug in DrugBank.

Gene name
F
UniProtKB entry
P11209Swiss-Prot
Cellular location
Host Golgi apparatus membrane
Residues / weight
574 residues · 63,334 Da

Resolves to

Protein
UniProtP11209UniProt nameFUS_HRSVR
Structure
PDB1G2C
Drugs

What you can answer from here — as of November 29, 2022

1DrugApproved to experimental, with action, bond type and pharmacological action
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9GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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2+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Fusion glycoprotein F0, how selective are they, and which programs against it are still in active trials?

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