Chloride anion exchanger

BE0010211ProteinHumansSLC26A3

Mediates chloride-bicarbonate exchange with a chloride bicarbonate stoichiometry of 2:1 in the intestinal epithelia (PubMed:16606687, PubMed:19321737, PubMed:22159084, PubMed:22627094). It is acted on by 1 drug in DrugBank.

Gene name
SLC26A3
UniProtKB entry
P40879Swiss-Prot
Cellular location
Apical cell membrane
Residues / weight
764 residues · 84,504 Da
Also known as
Down-regulated in adenoma · DRA · Protein DRA · Solute carrier family 26 member 3

Resolves to

Protein
UniProtP40879UniProt nameS26A3_HUMAN
Gene
HGNCHGNC:3018NCBI Gene1811GeneCardsSLC26A3
Pharmacology
KEGGhsa:1811
Structure
PDB7XUHPDB7XUJPDB7XUL
Drugs

What you can answer from here — as of January 24, 2023

1DrugApproved to experimental, with action, bond type and pharmacological action
Sign in
14GO termsFunction, process and component, as structured annotations
Sign in
2Pfam domainsDomain architecture mapped to Pfam families and clans
Sign in
2+ReferencesStructured and connected to the statements they support
Sign in

Which approved drugs act on Chloride anion exchanger, how selective are they, and which programs against it are still in active trials?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In