Thymidine kinase

BE0010219ProteinHuman herpesvirus 1 (strain KOS)TK

Catalyzes the transfer of the gamma-phospho group of ATP to thymidine to generate dTMP in the salvage pathway of pyrimidine synthesis. It is acted on by 1 drug in DrugBank.

Gene name
TK
UniProtKB entry
P17402Swiss-Prot
Residues / weight
376 residues · 40,927 Da
Also known as
2.7.1.21

Resolves to

Protein
UniProtP17402UniProt nameKITH_HHV1K
Drugs

What you can answer from here — as of April 28, 2023

1DrugApproved to experimental, with action, bond type and pharmacological action
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5GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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2+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Thymidine kinase, and which indications are they being tested in?

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