Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1

BE0010226ProteinHumansGPIHBP1

Mediates the transport of lipoprotein lipase LPL from the basolateral to the apical surface of endothelial cells in capillaries (By similarity). It is acted on by 1 drug in DrugBank.

Gene name
GPIHBP1
UniProtKB entry
Q8IV16Swiss-Prot
Cellular location
Apical cell membrane
Residues / weight
184 residues · 19,850 Da
Also known as
GPI-anchored HDL-binding protein 1 · GPI-HBP1 · HBP1 · High density lipoprotein-binding protein 1

Resolves to

Protein
UniProtQ8IV16UniProt nameHDBP1_HUMAN
Gene
HGNCHGNC:24945NCBI Gene338328GeneCardsGPIHBP1
Pharmacology
KEGGhsa:338328
Structure
PDB6E7KPDB6OAUPDB6OAZ
Drugs

What you can answer from here — as of July 20, 2023

1DrugApproved to experimental, with action, bond type and pharmacological action
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21GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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1+ReferenceStructured and connected to the statements they support
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Which approved drugs act on Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1, how selective are they, and which programs against it are still in active trials?

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