Cyclin-dependent kinase 3

BE0010230ProteinHumansCDK3

Serine/threonine-protein kinase that plays a critical role in the control of the eukaryotic cell cycle; involved in G0-G1 and G1-S cell cycle transitions. It is acted on by 1 drug in DrugBank.

Gene name
CDK3
UniProtKB entry
Q00526Swiss-Prot
Residues / weight
305 residues · 35,045 Da
Also known as
2.7.11.22 · CDKN3 · Cell division protein kinase 3

Resolves to

Protein
UniProtQ00526UniProt nameCDK3_HUMAN
Gene
HGNCHGNC:1772NCBI Gene1018GeneCardsCDK3
Pharmacology
IUPHAR/GtoPdb1975KEGGhsa:1018
Structure
PDB7XQKPDB8H4R
Drugs

What you can answer from here — as of July 27, 2023

1DrugApproved to experimental, with action, bond type and pharmacological action
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9GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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2+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Cyclin-dependent kinase 3, and which indications are they being tested in?

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