Platelet-derived growth factor subunit A

BE0010246ProteinHumansPDGFA

Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. It is acted on by 1 drug in DrugBank.

Gene name
PDGFA
UniProtKB entry
P04085Swiss-Prot
Cellular location
Secreted
Residues / weight
211 residues · 24,043 Da
Also known as
PDGF subunit A · PDGF-1 · PDGF1 · Platelet-derived growth factor A chain · Platelet-derived growth factor alpha polypeptide

Resolves to

Protein
UniProtP04085UniProt namePDGFA_HUMAN
Gene
HGNCHGNC:8799NCBI Gene5154GeneCardsPDGFA
Pharmacology
KEGGhsa:5154
Structure
PDB3MJK
Drugs

What you can answer from here — as of July 27, 2023

1DrugApproved to experimental, with action, bond type and pharmacological action
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4Clinical trialsTrials of drugs acting on it, by phase and status
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5GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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1+ReferenceStructured and connected to the statements they support
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Which compounds in development act on Platelet-derived growth factor subunit A, and which indications are they being tested in?

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