T-cell surface glycoprotein CD8 alpha chain

BE0010263ProteinHumansCD8A

Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses.

Gene name
CD8A
UniProtKB entry
P01732Swiss-Prot
Cellular location
Cell membrane
Residues / weight
235 residues · 25,729 Da
Also known as
MAL · T-lymphocyte differentiation antigen T8/Leu-2

Resolves to

Protein
UniProtP01732UniProt nameCD8A_HUMAN
Gene
HGNCHGNC:1706NCBI Gene925GeneCardsCD8A
Pharmacology
KEGGhsa:925
Structure
PDB1AKJPDB1CD8PDB1Q69

What you can answer from here — as of August 03, 2023

16Clinical trialsTrials of drugs acting on it, by phase and status
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2GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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Which compounds in development act on T-cell surface glycoprotein CD8 alpha chain, and which indications are they being tested in?

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