Granulocyte colony-stimulating factor

BE0010308ProteinHumansCSF3

Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. It is acted on by 1 drug in DrugBank.

Gene name
CSF3
UniProtKB entry
P09919Swiss-Prot
Cellular location
Secreted
Residues / weight
207 residues · 22,293 Da
Also known as
C17orf33 · G-CSF · GCSF · Pluripoietin

Resolves to

Protein
UniProtP09919UniProt nameCSF3_HUMAN
Gene
HGNCHGNC:2438NCBI Gene1440GeneCardsCSF3
Pharmacology
KEGGhsa:1440
Structure
PDB1CD9PDB1GNCPDB1PGR
Drugs

What you can answer from here — as of October 31, 2023

1DrugApproved to experimental, with action, bond type and pharmacological action
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38Clinical trialsTrials of drugs acting on it, by phase and status
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3GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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1+ReferenceStructured and connected to the statements they support
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Which approved drugs act on Granulocyte colony-stimulating factor, how selective are they, and which programs against it are still in active trials?

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