Programmed cell death 1 ligand 2

BE0010315ProteinHumansPDCD1LG2

Plays a critical role in induction and maintenance of immune tolerance to self (PubMed:11224527, PubMed:12538684). It is acted on by 1 drug in DrugBank.

Gene name
PDCD1LG2
UniProtKB entry
Q9BQ51Swiss-Prot
Cellular location
Secreted
Residues / weight
273 residues · 30,957 Da
Also known as
B7-DC · B7DC · Butyrophilin B7-DC · CD273 · PD-1 ligand 2

Resolves to

Protein
UniProtQ9BQ51UniProt namePD1L2_HUMAN
Gene
HGNCHGNC:18731NCBI Gene80380GeneCardsPDCD1LG2
Pharmacology
KEGGhsa:80380
Structure
PDB6UMTPDB8J3V
Drugs

What you can answer from here — as of October 31, 2023

1DrugApproved to experimental, with action, bond type and pharmacological action
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43Clinical trialsTrials of drugs acting on it, by phase and status
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4GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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1+ReferenceStructured and connected to the statements they support
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Which compounds in development act on Programmed cell death 1 ligand 2, and which indications are they being tested in?

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