Transcription factor Sp1

BE0010335ProteinHumansSP1

Transcription factor that can activate or repress transcription in response to physiological and pathological stimuli. It is acted on by 2 drugs in DrugBank.

Gene name
SP1
UniProtKB entry
P08047Swiss-Prot
Cellular location
Nucleus
Residues / weight
785 residues · 80,693 Da
Also known as
TSFP1

Resolves to

Protein
UniProtP08047UniProt nameSP1_HUMAN
Gene
HGNCHGNC:11205NCBI Gene6667GeneCardsSP1
Pharmacology
KEGGhsa:6667
Structure
PDB1SP1PDB1SP2PDB1VA1
Drugs

What you can answer from here — as of October 31, 2023

2DrugsApproved to experimental, with action, bond type and pharmacological action
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1Clinical trialTrials of drugs acting on it, by phase and status
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2GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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2+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Transcription factor Sp1, and which indications are they being tested in?

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