Tenascin

BE0010336ProteinHumansTNC

Extracellular matrix protein implicated in guidance of migrating neurons as well as axons during development, synaptic plasticity as well as neuronal regeneration. It is acted on by 2 drugs in DrugBank.

Gene name
TNC
UniProtKB entry
P24821Swiss-Prot
Cellular location
Secreted, extracellular space, extracellular matrix
Residues / weight
2,201 residues · 240,851 Da
Also known as
Cytotactin · Glioma-associated-extracellular matrix antigen · GMEM · GP 150-225 · Hexabrachion

Resolves to

Protein
UniProtP24821UniProt nameTENA_HUMAN
Gene
HGNCHGNC:5318NCBI Gene3371GeneCardsTNC
Pharmacology
KEGGhsa:3371
Structure
PDB1TENPDB2RB8PDB2RBL
Drugs

What you can answer from here — as of October 31, 2023

2DrugsApproved to experimental, with action, bond type and pharmacological action
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4Clinical trialsTrials of drugs acting on it, by phase and status
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4GO termsFunction, process and component, as structured annotations
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6Pfam domainsDomain architecture mapped to Pfam families and clans
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3+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Tenascin, and which indications are they being tested in?

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