G2/mitotic-specific cyclin-B1

BE0010356ProteinHumansCCNB1

Essential for the control of the cell cycle at the G2/M (mitosis) transition (PubMed:27030811, PubMed:17495531, PubMed:17495533). It is acted on by 1 drug in DrugBank.

Gene name
CCNB1
UniProtKB entry
P14635Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
433 residues · 48,337 Da
Also known as
CCNB

Resolves to

Protein
UniProtP14635UniProt nameCCNB1_HUMAN
Gene
HGNCHGNC:1579NCBI Gene891GeneCardsCCNB1
Pharmacology
KEGGhsa:891
Structure
PDB2B9RPDB2JGZPDB4Y72
Drugs

What you can answer from here — as of October 31, 2023

1DrugApproved to experimental, with action, bond type and pharmacological action
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3Clinical trialsTrials of drugs acting on it, by phase and status
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2GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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1+ReferenceStructured and connected to the statements they support
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Which compounds in development act on G2/mitotic-specific cyclin-B1, and which indications are they being tested in?

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