Syndecan-1

BE0010357ProteinHumansSDC1

Cell surface proteoglycan that contains both heparan sulfate and chondroitin sulfate and that links the cytoskeleton to the interstitial matrix (By similarity). It is acted on by 3 drugs in DrugBank.

Gene name
SDC1
UniProtKB entry
P18827Swiss-Prot
Cellular location
Membrane
Residues / weight
310 residues · 32,461 Da
Also known as
SDC · SYND1

Resolves to

Protein
UniProtP18827UniProt nameSDC1_HUMAN
Gene
HGNCHGNC:10658NCBI Gene6382GeneCardsSDC1
Pharmacology
KEGGhsa:6382
Structure
PDB4GVCPDB4GVDPDB6EJE
Drugs

What you can answer from here — as of October 31, 2023

3DrugsApproved to experimental, with action, bond type and pharmacological action
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9Clinical trialsTrials of drugs acting on it, by phase and status
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1GO termFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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6+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Syndecan-1, and which indications are they being tested in?

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