Hematopoietic progenitor cell antigen CD34

BE0010381ProteinHumansCD34

Possible adhesion molecule with a role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. It is acted on by 3 drugs in DrugBank.

Gene name
CD34
UniProtKB entry
P28906Swiss-Prot
Cellular location
Membrane
Residues / weight
385 residues · 40,716 Da

Resolves to

Protein
UniProtP28906UniProt nameCD34_HUMAN
Gene
HGNCHGNC:1662NCBI Gene947GeneCardsCD34
Pharmacology
KEGGhsa:947
Drugs

What you can answer from here — as of October 31, 2023

3DrugsApproved to experimental, with action, bond type and pharmacological action
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205Clinical trialsTrials of drugs acting on it, by phase and status
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1Pfam domainDomain architecture mapped to Pfam families and clans
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7+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Hematopoietic progenitor cell antigen CD34, how selective are they, and which programs against it are still in active trials?

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