N-myc proto-oncogene protein

BE0010382ProteinHumansMYCN

Positively regulates the transcription of MYCNOS in neuroblastoma cells. It is acted on by 1 drug in DrugBank.

Gene name
MYCN
UniProtKB entry
P04198Swiss-Prot
Cellular location
Nucleus
Residues / weight
464 residues · 49,561 Da
Also known as
BHLHE37 · Class E basic helix-loop-helix protein 37 · NMYC

Resolves to

Protein
UniProtP04198UniProt nameMYCN_HUMAN
Gene
HGNCHGNC:7559NCBI Gene4613GeneCardsMYCN
Pharmacology
KEGGhsa:4613
Structure
PDB5G1XPDB7ZTL
Drugs

What you can answer from here — as of October 31, 2023

1DrugApproved to experimental, with action, bond type and pharmacological action
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13Clinical trialsTrials of drugs acting on it, by phase and status
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2GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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3+ReferencesStructured and connected to the statements they support
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Which compounds in development act on N-myc proto-oncogene protein, and which indications are they being tested in?

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