Glial fibrillary acidic protein

BE0010385ProteinHumansGFAP

GFAP, a class-III intermediate filament, is a cell-specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells. It is acted on by 1 drug in DrugBank.

Gene name
GFAP
UniProtKB entry
P14136Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
432 residues · 49,880 Da
Also known as
GFAP

Resolves to

Protein
UniProtP14136UniProt nameGFAP_HUMAN
Gene
HGNCHGNC:4235NCBI Gene2670GeneCardsGFAP
Pharmacology
KEGGhsa:2670
Structure
PDB6A9P
Drugs

What you can answer from here — as of October 31, 2023

1DrugApproved to experimental, with action, bond type and pharmacological action
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2Clinical trialsTrials of drugs acting on it, by phase and status
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4GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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1+ReferenceStructured and connected to the statements they support
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Which approved drugs act on Glial fibrillary acidic protein, how selective are they, and which programs against it are still in active trials?

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