Receptor-type tyrosine-protein phosphatase C

BE0010406ProteinHumansPTPRC

Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor (PubMed:35767951). It is acted on by 2 drugs in DrugBank.

Gene name
PTPRC
UniProtKB entry
P08575Swiss-Prot
Cellular location
Cell membrane
Residues / weight
1,306 residues · 147,485 Da
Also known as
3.1.3.48 · CD45 · L-CA · Leukocyte common antigen · T200

Resolves to

Protein
UniProtP08575UniProt namePTPRC_HUMAN
Gene
HGNCHGNC:9666NCBI Gene5788GeneCardsPTPRC
Pharmacology
KEGGhsa:5788
Structure
PDB1YGRPDB1YGUPDB5FMV
Drugs

What you can answer from here — as of October 31, 2023

2DrugsApproved to experimental, with action, bond type and pharmacological action
Sign in
28Clinical trialsTrials of drugs acting on it, by phase and status
Sign in
60GO termsFunction, process and component, as structured annotations
Sign in
4Pfam domainsDomain architecture mapped to Pfam families and clans
Sign in
4+ReferencesStructured and connected to the statements they support
Sign in

Which approved drugs act on Receptor-type tyrosine-protein phosphatase C, how selective are they, and which programs against it are still in active trials?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In