Thrombospondin-1

BE0010410ProteinHumansTHBS1

Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions (PubMed:15014436, PubMed:18285447, PubMed:2430973, PubMed:6489349). It is acted on by 4 drugs in DrugBank.

Gene name
THBS1
UniProtKB entry
P07996Swiss-Prot
Cellular location
Secreted
Residues / weight
1,170 residues · 129,382 Da
Also known as
Glycoprotein G · TSP · TSP1

Resolves to

Protein
UniProtP07996UniProt nameTSP1_HUMAN
Gene
HGNCHGNC:11785NCBI Gene7057GeneCardsTHBS1
Pharmacology
KEGGhsa:7057
Structure
PDB1LSLPDB1UX6PDB1Z78
Drugs

What you can answer from here — as of October 31, 2023

4DrugsApproved to experimental, with action, bond type and pharmacological action
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14Clinical trialsTrials of drugs acting on it, by phase and status
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9GO termsFunction, process and component, as structured annotations
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4Pfam domainsDomain architecture mapped to Pfam families and clans
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4+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Thrombospondin-1, and which indications are they being tested in?

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