Fibroblast growth factor 23

BE0010448ProteinHumansFGF23

Regulator of phosphate homeostasis (PubMed:11062477). It is acted on by 1 drug in DrugBank.

Gene name
FGF23
UniProtKB entry
Q9GZV9Swiss-Prot
Cellular location
Secreted
Residues / weight
251 residues · 27,954 Da
Also known as
FGF-23 · HYPF · Phosphatonin · Tumor-derived hypophosphatemia-inducing factor

Resolves to

Protein
UniProtQ9GZV9UniProt nameFGF23_HUMAN
Gene
HGNCHGNC:3680NCBI Gene8074GeneCardsFGF23
Pharmacology
KEGGhsa:8074
Structure
PDB2P39PDB5W21PDB6S22
Drugs

What you can answer from here — as of October 31, 2023

1DrugApproved to experimental, with action, bond type and pharmacological action
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5Clinical trialsTrials of drugs acting on it, by phase and status
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2GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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5+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Fibroblast growth factor 23, how selective are they, and which programs against it are still in active trials?

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