Wilms tumor protein

BE0010449ProteinHumansWT1

Transcription factor that plays an important role in cellular development and cell survival (PubMed:7862533). It is acted on by 4 drugs in DrugBank.

Gene name
WT1
UniProtKB entry
P19544Swiss-Prot
Cellular location
Nucleus
Residues / weight
449 residues · 49,188 Da
Also known as
WT33

Resolves to

Protein
UniProtP19544UniProt nameWT1_HUMAN
Gene
HGNCHGNC:12796NCBI Gene7490GeneCardsWT1
Pharmacology
KEGGhsa:7490
Structure
PDB1XF7PDB2JP9PDB2JPA
Drugs

What you can answer from here — as of October 31, 2023

4DrugsApproved to experimental, with action, bond type and pharmacological action
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17Clinical trialsTrials of drugs acting on it, by phase and status
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1GO termFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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7+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Wilms tumor protein, and which indications are they being tested in?

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